What is the sterilization process of cosmetic packaging bottles?


Aiming at the defects in the sterilization and disinfec […]

Aiming at the defects in the sterilization and disinfection field of cosmetic packaging bottles in the cosmetics industry in China for many years, the old technology has been used for reference, the international advanced disinfection industry is used for reference, the "GMP Verification Guidelines" and the "disinfection technical specifications" requirements formulated by the Ministry of Health are designed and manufactured "JZCF-B" series packaging container ozone disinfection system, the disinfection effect is obvious. Cosmetic packaging containers require advanced sterilization process analysis;
The principle of ozone sterilization
The sterilization category of ozone belongs to the biochemical oxidation reaction. Ozone oxidation decomposes the enzymes necessary for the oxidation of glucose in bacteria; it can also directly interact with bacteria and viruses, destroy their cell walls and ribonucleic acid, decompose DNA, RNA, proteins, lipids and polysaccharides and other macromolecular polymers to make bacteria The material metabolism, growth and reproduction process of the cell is destroyed; it can also penetrate the cell membrane tissue, invade the cell membrane and act on the outer membrane lipoprotein and internal lipopolysaccharide, causing the cell to undergo permeability aberrations, leading to cell lysis and death, and will die The genetic genes, parasitic strains, parasitic virus particles, bacteriophages, mycoplasma and pyrogens (bacterial virus metabolites, endotoxins) in the bacteria dissolve, denature and die. Throughout the principle of aseptic technology on microorganisms, it can be divided into three types: bacteriostasis, sterilization and bacteriolysis. The application of ozone as a sterilizing agent belongs to bacteriolysis.
In the "Disinfection Technical Specifications" promulgated by the Ministry of Health in 1991, there is also an introduction to the principle of ozone sterilization:
"Scientific research shows that ozone has a strong bactericidal effect." "The molecular structure of ozone is unstable under normal temperature and pressure, and it quickly decomposes into oxygen and single oxygen atoms. The latter has strong activity and is extremely active against bacteria. Strong oxidation. Ozone oxidation decomposes the enzymes necessary to oxidize glucose inside the bacteria, thereby destroying the cell membrane and killing it. The excess oxygen atoms will recombine themselves into ordinary oxygen molecules without any toxic residues, so it is called 'Non-pollution disinfectant'. It not only has a strong ability to kill all kinds of bacteria (including hepatitis virus, E. coli, Pseudomonas aeruginosa and other bacteria, etc.), it is also very effective in killing molds."

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