On the sterilization process of cosmetic packaging bottles

Update:28-02-2020
Summary:

Aiming at the sterilization and sterilization of cosmet […]

Aiming at the sterilization and sterilization of cosmetic packaging bottles in the cosmetics industry in China for many years, the old technology has been used and there are defects. Drawing on the international advanced sterilization industry, we follow the requirements of the "GMP Verification Guide" and "Disinfection Technical Specifications" formulated by the Ministry of Health. The "JZCF-B" series packaging container ozone disinfection system has obvious disinfection effect. Cosmetic packaging containers require advanced sterilization process analysis;
First, the principle of ozone sterilization
    Ozone sterilization belongs to the biochemical oxidation reaction. Ozone oxidation decomposes the enzymes necessary for oxidizing glucose inside bacteria; it can also directly interact with bacteria and viruses, destroy its cell wall and ribonucleic acid, and break down macromolecular polymers such as DNA, RNA, proteins, lipids and polysaccharides, making bacteria The material metabolism growth and reproduction process is damaged; it can also penetrate cell membrane tissues, invade cell membranes and act on outer membrane lipoproteins and internal lipopolysaccharides, causing cells to undergo permeation distortion, resulting in cell lysis and death, and death The genetic genes, parasitic bacteria species, parasitic virus particles, phages, mycoplasma, and pyrogens (bacterial virus metabolites, endotoxins) in the bacteria are dissolved and destructed. The principle of aseptic technology on microorganisms can be divided into three types: bacteriostatic, bactericidal and lysolytic. The application of ozone as a sterilizing agent belongs to lysobacteria.
In the "Technical Specification for Disinfection" promulgated by the Ministry of Health in 1991, there is also an introduction to the principle of sterilization of ozone:
"Scientific research shows that ozone has a very strong bactericidal effect." "Ozone has an unstable molecular structure at room temperature and pressure, and quickly decomposes itself into oxygen and single oxygen atoms. Strong oxidative effect. Ozone oxidation breaks down the enzymes necessary for oxidizing glucose inside bacteria, thereby destroying the cell membrane and killing it. The excess oxygen atoms will recombine themselves into ordinary oxygen molecules without any toxic residue. 'Pollution-free disinfectant'. It is not only very effective in killing all kinds of bacteria (including hepatitis virus, E.coli, Pseudomonas aeruginosa and miscellaneous bacteria), but also very effective in killing mold. "